Most platforms claim results.
Ours are peer-reviewed.
From early feasibility studies to real-world evidence and active clinical trials, our platform has been evaluated, validated, and recognized by leading academic medical centers and research institutions.
Synchronyx generates peer-reviewed and real-world evidence for real-time medication adherence monitoring, treatment persistence, patient-reported outcomes, and workflow-ready digital engagement across specialty and chronic care.
Real-World Evidence Across Studies
90.7%
Average Adherence
83.5%
1-Year Engagement
58.6%
Reduction in Side Effects
44.5%
Improvement in Symptom Severity Score
75.4
System Usability Score
Exceeds benchmarks
Evidence by Disease Area
Oncology
Peer-reviewed evidence and real-world data supporting adherence monitoring, symptom reporting, and timely care team intervention in oral oncology and cancer care navigation programs.
Inflammatory Bowel Disease
Controlled clinical research and real-world evidence supporting adherence monitoring, PRO capture, and care team alerting across oral, subcutaneous, and intravenous IBD therapies, from investigator-initiated trials to pharma-supported multi-center studies.
Infectious Disease
Real-world evidence and active registered research supporting antiretroviral therapy adherence, HIV care engagement, and HCV treatment monitoring through multi-faceted remote interventions across clinical and community settings.
Cardiovascular and Renal Care
Active registered research using Tappt as a real-time electronic diary and remote monitoring tool in procedural and interventional care settings, extending the platform's evidence base beyond chronic disease management.
Remote Therapeutic Monitoring
Peer-reviewed analysis of RTM reimbursement policy and its implications for case management, specialty pharmacy, and care delivery teams managing patients on complex medication regimens.
Publications and Presentations
Peer-Reviewed Publications
Graetz I, Arshad S, Cai C, Hernandez S, Sapir T, Carter J, Heggen C, McKinnon KE, Yang F, Sadigh G, Meisel J. Feasibility of a Smart Label-Enabled Remote Therapeutic Monitoring Intervention to Support Cyclin-Dependent Kinase 4/6 Inhibitor Adherence in Breast Cancer Care. JCO Clinical Cancer Informatics. 2025;9:e2500152. Read the full paper →
Axelrad J, Long M, Horst S, Afzali A, Sapir T, Fajardo K, De Felice K, Sandler R, Cross R. A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and Persistence With Inflammatory Bowel Disease Therapy (ASSIST Study): Protocol for a Randomized Controlled Trial. JMIR Research Protocols. 2022;11(12):e40382. Read the full paper →
Moreo K, Sapir T. Growth of Remote Therapeutic Monitoring Lands New Opportunities for Case Management. Professional Case Management. 2024;29(2):63-69. PMID: 38015812. Read on PubMed →
Award-Winning Presentations
Axelrad J, Sapir T, Horst SN, DeFelice K, Afzali A, Abdelrehem A, Noyes A, Anderson C, Long MD, Cross RK. A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and Persistence With Inflammatory Bowel Disease Therapy: Updates From the ASSIST Study. The American Journal of Gastroenterology. 2024;119(10S):S865-S867. American College of Gastroenterology Annual Scientific Meeting, October 2024. 🏆 Award-Winning Presentation Read the abstract →
Axelrad J, Sapir T, Horst S, DeFelice K, Afzali A, Noyes A, Abdelrehem A, Anderson C, Long M, Cross R. A Novel Remote Patient and Therapeutic Monitoring Solution to Improve Adherence and Persistence with Inflammatory Bowel Disease Therapy: Updates from the ASSIST Study. American Telemedicine Association Annual Meeting, 2025. 🏆 Award-Winning Presentation
Arshad S, Sapir T, Carter J, Heggen C, McKinnon K, Cai C, Yang F, Sadigh G, Meisel J, Graetz I. Feasibility Trial of the Systematic Monitoring and Adherence Realization for Treatment in Hormone Receptor-Positive Breast Cancer (SMART Reach). Journal of the American Pharmacists Association. 2025;65(3):102398. Pharmacy Quality Alliance Annual Meeting, May 2025, Tampa, FL. 🥇 Gold Medal Winner
Conference Abstracts and Presentations
Meisel J, Sapir T, Graetz I, Arshad S, Rodriguez M, Dooyema S, Carter J, Heggen C, McKinnon K. Improving Adherence to CDK4/6 Inhibitors in Breast Cancer Through Remote Therapeutic Monitoring with Real-Time Adherence Tracking and Actionable Alerts. Journal of Clinical Oncology. 2025;43(16 suppl):e12520. ASCO Annual Meeting, 2025. Read the abstract →
Sapir T, Beckmann L, Arshad S, Carter J, Heggen C, McKinnon K, Meisel J, Graetz I. The Role of Social Determinants of Health in Medication Adherence for CDK4/6 Inhibitors in Breast Cancer: Insights From a Remote Monitoring Tool. Journal of the American Pharmacists Association. 2025;65(3):102398. Pharmacy Quality Alliance Annual Meeting, May 2025, Tampa, FL.
Hightow-Weidman L, Sapir T, Molloy L, Simone L, Napolitan C, Carter J, Rodriguez M, Anderson Chadha C, Pillinger KE. Improving ART Adherence and HIV Care Engagement Through Multi-Faceted Interventions. IDWeek, October 2025. Abstract #2112329.
Active Registered Clinical Trials
SMART Study Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy: A Pilot Feasibility Clinical Trial. Conducted at UC Irvine Chao Family Comprehensive Cancer Center. ClinicalTrials.gov ID: NCT07073807. View registration →
ASSIST Study A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and Persistence With Inflammatory Bowel Disease Therapy. ClinicalTrials.gov ID: NCT05316584.
MONITOR Study Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients with Inflammatory Bowel Disease Using a Novel Remote Monitoring Intervention. Supported by Takeda Pharmaceuticals. Conducted across 7 IBD centers. ClinicalTrials.gov ID: NCT06750731. View registration →
HCV Tappt Adherence Study ClinicalTrials.gov ID: NCT06263829. View registration →
Renal Pelvic Denervation Pilot Trial ClinicalTrials.gov ID: NCT07005050. View registration →